Gastrointestinal Disease in the Hemolytic-Uremic Syndrome

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Hemolytic uremic syndrome in children: Seizure disorders and mortality rate

Background and Objective: Hemolytic Uremic Syndrome (HUS) is a thrombotic microangiopathy that contains hemolytic anemia, thrombocytopenia, renal failure and other organ involvement including central nervous system. Frequency of neurologic complications in patients with HUS is high and important cause of mortality. This study was performed to determine seizure disorders in term of acute neurolo...

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Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy (TMA) characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. Most cases of aHUS are caused by uncontrolled complement activation due to genetic mutations in the alternative pathway of complement. More recently, mutations in the gene of coagulation system have also been identified in...

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Hemolytic uremic syndrome (HUS) is a triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. The atypical form of HUS is a disease characterized by complement overactivation. Inherited defects in complement genes and acquired autoantibodies against complement regulatory proteins have been described. Incomplete penetrance of mutations in all predisposing genes is r...

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ژورنال

عنوان ژورنال: Gastroenterology

سال: 1979

ISSN: 0016-5085

DOI: 10.1016/s0016-5085(79)80172-9